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You searched for: creator:"Chen, M"
[texts]A log periodic monopole antenna final report - Chen, M.
Log periodic monopole antenna - computer analysis and radiation pattern
Downloads: 233
[texts]Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells. (Volume 5) - Hsu, Y-C
This article is from Cell Death & Disease, volume 5.AbstractCucurbitacin E (CuE) is a natural compound previously shown to have anti-feedant, antioxidant and antitumor activities as well as a potent chemo-preventive action against cancer. The present study investigates its anti-proliferative property using MTT assay; CuE demonstrated cytotoxic activity against malignant glioma GBM 8401 cells and induced cell cycle G2/M arrest in these cells...
Downloads: 3
[texts]Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E. (Volume 5) - Hsu, Y-C
This article is from Cell Death & Disease, volume 5.AbstractCucurbitacin E (CuE) or α-elaterin is a natural compound previously shown to be an antifeedant as well as a potent chemopreventive agent against several types of cancer. The present study investigated the anticancer effects of CuE on colorectal cancer (CRC) using primary cell lines isolated from five CRC patients in Taiwan, Specifically, we explored the anti-proliferation and cell cycle G2/M arrest induced by CuE in CRC cells...
Downloads: 2
[texts]Endowment effect in capuchin monkeys. (Volume 363) - Lakshminaryanan, Venkat
This article is from Philosophical Transactions of the Royal Society B: Biological Sciences, volume 363.AbstractIn humans, the capacity for economically rational choice is constrained by a variety of preference biases: humans evaluate gambles relative to arbitrary reference points; weigh losses heavier than equally sized gains; and demand a higher price for owned goods than for equally preferred goods that are not yet owned...
Downloads: 1
[texts]The effect Akt2 deletion on tumor development in Pten+/− mice. (Volume 31) - Xu, P-Z
This article is from Oncogene, volume 31.AbstractThe serine/threonine kinase Akt is frequently activated in human cancers and is considered an attractive therapeutic target. However, the relative contributions of the different Akt isoforms to tumorigenesis, and the effect of their deficiencies on cancer development are not well understood. We had previously shown that Akt1 deficiency is sufficient to markedly reduce the incidence of tumors in Pten+/− mice...
Downloads: 2
[texts]Minimizing shoulder syndrome with intra-operative spinal accessory nerve monitoring for neck dissection. (Volume 33) - LEE, C.-H.
This article is from Acta Otorhinolaryngologica Italica, volume 33.AbstractThe objective of this study was to analyze the safety and results of intra-operative SAN (spinal accessary nerve) monitoring during selective neck dissection, with emphasis on shoulder syndrome. Twenty-five consecutive patients with head and neck cancer were studied. Selective neck dissection was performed by a single clinical fellow under the supervision of the department chief using an intra-operative SAN monitor...
Downloads: 5
[texts]The prognostic value of CDKN2A hypermethylation in colorectal cancer: a meta-analysis. (Volume 108) - Xing, X
This article is from British Journal of Cancer, volume 108.AbstractBackground:: The prognostic value of CDKN2A promoter hypermethylation in colorectal cancer remains controversial. We systematically reviewed the evidence for assessment of CDKN2A methylation in colorectal cancer to elucidate this issue. Methods:: Pubmed, Embase and ISI web of knowledge were searched to identify eligible studies to evaluate the association of CDKN2A hypermethylation and overall survival and clinicopathological fea...
Downloads: 9
[texts]Association of p21 with NF-YA suppresses the expression of Polo-like kinase 1 and prevents mitotic death in response to DNA damage. (Volume 5) - Lin, Y-C
This article is from Cell Death & Disease, volume 5.AbstractPolo-like kinase 1 (PLK1) is an important mitotic kinase and its expression is tightly regulated in the cell cycle and in the DNA damage response. PLK1 expression is previously shown to be suppressed by p53 and/or p21. Here, we demonstrate that the CCAAT box in the PLK1 promoter is pivotal for p53/p21-mediated PLK1 repression. Chromatin immunoprecipitation showed that cyclin-dependent kinase 2 (CDK2) associated with the CCAAT box-contai...
Downloads: 4
[texts]Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state. (Volume 2) - Zhang, Y
This article is from Cell Death & Disease, volume 2.AbstractIsthmin (ISM) is a 60 kDa secreted-angiogenesis inhibitor that suppresses tumor growth in mouse and disrupts vessel patterning in zebrafish embryos. It selectively binds to alphavbeta5 (αvβ5) integrin on the surface of endothelial cells (ECs), but the mechanism of its antiangiogenic action remains unknown. In this work, we establish that soluble ISM suppresses in vitro angiogenesis and induces EC apoptosis by interacting with its ce...
Downloads: 2
[texts]An investigation of the effectiveness of existing bridge design methodology in providing adequate structural resistance to seismic disturbances. Phase III : analytical investigations of seismic response of short, single, or multiple-span highway bridges - Chen, M
Prepared for U. S. Federal Highway Administration; its R&D report no. S-0314
Downloads: 67
[texts]The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells. (Volume 4) - Chen, M-C
This article is from Cell Death & Disease, volume 4.AbstractEpidermal growth factor receptor (EGFR), which promotes cell survival and division, is found at abnormally high levels on the surface of many cancer cell types, including many cases of non-small cell lung cancer. Erlotinib (Tarceva), an oral small-molecule tyrosine kinase inhibitor, is a so-called targeted drug that inhibits the tyrosine kinase domain of EGFR, and thus targets cancer cells with some specificity while doing less damage t...
Downloads: 3
[texts]Detection of acute cerebral hemorrhage in rabbits by magnetic induction. (Volume 47) - Sun, J.
This article is from Brazilian Journal of Medical and Biological Research, volume 47.AbstractAcute cerebral hemorrhage (ACH) is an important clinical problem that is often monitored and studied with expensive devices such as computed tomography, magnetic resonance imaging, and positron emission tomography. These devices are not readily available in economically underdeveloped regions of the world, emergency departments, and emergency zones...
Downloads: 2
[texts]Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. (Volume 102) - Xu, C-F
This article is from British Journal of Cancer, volume 102.AbstractBackground:: Pazopanib has shown clinical activity against multiple tumour types and is generally well tolerated. However, isolated elevations in transaminases and bilirubin have been observed. This study examined polymorphisms in molecules involved in pharmacokinetic and pharmacodynamic pathways of pazopanib and their association with hepatic dysfunction...
Downloads: 2
[movies]Hubble Spies Brown Dwarfs in Nearby Stellar Nursery - *Credits for near-infrared image:* NASA [ ]; K.L. Luhman (Harvard-Smithsonian Center for Astrophysics, Cambridge, Mass.); and G. Schneider, E. Young, G. Rieke, A. Cotera, H. Chen, M. Rieke, R. Thompson (Steward Observatory, University of Arizona, Tucson, Ariz.) *Credits for visible-light picture:* NASA [ ], C.R. O'Dell and S.K. Wong (Rice University)
*Description*: Probing deep within a neighborhood stellar nursery, NASA's Hubble Space Telescope uncovered a swarm of newborn brown dwarfs. The orbiting observatory's near-infrared camera revealed about 50 of these objects throughout the Orion Nebula's Trapezium cluster [image at right], about 1,500 light-years from Earth. Appearing like glistening precious stones surrounding a setting of sparkling diamonds, more than 300 fledgling stars and brown dwarfs surround the brightest, most massive star...
Keywords: NGC 1976; M42; Orion Nebula; What -- Hubble Space Telescope (HST); What -- Near Infrared Camera and Multi-Object Spectrometer (NICMOS); What -- Camera 2; What -- Orion; What -- Earth; What -- FUSE; What -- Sun; What -- Visible Light; What -- Spectrometer
Downloads: 104
[texts]Consistency of predictive signature genes and classifiers generated using different microarray platforms. (Volume 10) - Fan, X
This article is from The Pharmacogenomics Journal, volume 10.AbstractMicroarray-based classifiers and associated signature genes generated from various platforms are abundantly reported in the literature; however, the utility of the classifiers and signature genes in cross-platform prediction applications remains largely uncertain. As part of the MicroArray Quality Control Phase II (MAQC-II) project, we show in this study 80–90% cross-platform prediction consistency using a large toxicogenomic...
Downloads: 2
[texts]Functional analysis of multiple genomic signatures demonstrates that classification algorithms choose phenotype-related genes. (Volume 10) - Shi, W
This article is from The Pharmacogenomics Journal, volume 10.AbstractGene expression signatures of toxicity and clinical response benefit both safety assessment and clinical practice; however, difficulties in connecting signature genes with the predicted end points have limited their application. The Microarray Quality Control Consortium II (MAQCII) project generated 262 signatures for ten clinical and three toxicological end points from six gene expression data sets, an unprecedented collection...
Downloads: 1
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